Information On Lupron Fertility
Physicians usually prescribe lupron i.e. leuprolide acetate for the treatment of
endometriosis. It is considered capable of lowering the estrogen levels and FSH
and LH (lutenizing hormone) production in the body is down regulated.
Endometrial tissue relies greatly upon estrogen for growth.
It is also used as a Lupron fertility drug in IVF (invitro fertilization) as per patient’s
particular protocols. Generally, it is given along with a follicle-stimulating
hormone (FSH). It is a GnRH- agonist, which works against the body’s naturally
occurring gonadotropin-releasing hormone. Thus, it proves helpful in stimulating
egg production for an IVF cycle.
The type of protocol is decided according to the physical history of patient.
Everything including the current type of treatment, physician’s preferences etc.
are taken into consideration. Mostly these protocols are either luteal lupron or
flare protocols.
Lupron is given several days in advance of next expected period of patient.
Larger doses of lupron are given till the FSH medicine is not included to the
protocol and the dose varies. This kind of protocol is considered best to provide
women with the best possible number of mature follicles. It, in turn is taken as the
best predictor of informing the possibility of success of IVF. For poor responders,
the flare protocol is generally used. With the first administration of lupron, there
remains initial increase in FSH for number of days, which is followed by
suppression. On the second day of period, lupron is administered and FSH is
added, taking advantage of this surge in FSH,
Since, ovulation cannot take place while on lupron, as the lupron blocks body’s
natural FSH and LH; it prevents a premature surge of LH prior to retrieval. Thus,
the patient is given with a synthetic form of the FSH. It is given to ensure the
occurrence of development and maturation of follicle.
Lupron is administered either by intramuscular injection (IM) or by subcutaneous
injection. Subcutaneous injection is given once in a day by using insulin syringe.
Often, one vial is sufficient for one treatment cycle. Also, the patient is provided
with a prescription for insulin syringes. This medicine must be refrigerated.
This medicine is administered on either thigh area or abdomen. Before
administering, the area is cleaned with alcohol. Thereafter, using thumb and first
finger area is spread and the medicine is injected. The needle is pulled out and
gauze is used to rub the area softly.
Like lupron fertility drug, ganirelix acetate and cetrotide acetate also perform
function of suppressing FSH and LH production. But here the suppression is
more complete than lupron.
Side effects that may occur due to the usage of lupron include headache,
irritability, forgetfulness, breast tenderness, vaginal dryness, irritation at injection
area and ovarian cyst formation.
However, lupron helps in preparing the ovaries for stimulation in conjunction with
other fertility medicines.
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